http://bugs.winehq.org/show_bug.cgi?id=59043
--- Comment #2 from Terry Coles winehq@hadrian-way.co.uk --- I didn't do that, but I just did after first uninstalling wine and attempting to uninstall the i386 architecture. I got:
sudo dpkg --remove-architecture i386 [sudo] password for terry: dpkg: error: cannot remove architecture 'i386' currently in use by the database
This was after a reboot.