https://bugs.winehq.org/show_bug.cgi?id=41136
--- Comment #1 from fjfrackiewicz@gmail.com --- "winetricks vcrun2015" works around the problem if it is ran before attempting to install Galaxy.
I did try installing in a clean WoW64 prefix and I managed to install Galaxy but Windows XP, when in 64-bits, is either missing Service Pack 3 or the 64-bit version of XP never got a third service pack. This is a problem since Galaxy quits with a message stating that Windows XP SP 3 is the minimum required OS to run Galaxy.
Not sure whether this is a valid bug or not for another report entirely...