Dear Dan,
I agree that it would be nice to have a command-line interface for wine settings cause I have run into situations that I have to configure wine before going into X. So is it possible to first group/rearrange winecfg functions into certain libraries and then let the GUI (control panel) and the CLI all interact with the corresponding libraries?
About winetricks, I do not know much about it. What exactly do you mean by "winetricks settings"?